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No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees. Plus, our Low Price Guarantee! No Avoya Fees on Cruises or Tours.
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MSC Cruises to South America
MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.
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7-night south america cruise
$1,060
50% Off List
MSC Cruises –
MSC Virtuosa
Departs
Mar 17, 2027
from
MACEIO
Up to 1 deal
8-night south america cruise
$1,249
49% Off List
MSC Cruises –
MSC Splendida
Departs
Mar 18, 2027
from
Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$1,085
49% Off List
MSC Cruises –
MSC Virtuosa
Departs
Mar 20, 2027
from
Santos, Brazil
Up to 1 deal
7-night south america cruise
$1,060
50% Off List
MSC Cruises –
MSC Virtuosa
Departs
Mar 23, 2027
from
Salvador, Brazil
Up to 1 deal
8-night south america cruise
$1,326
50% Off List
MSC Cruises –
MSC Splendida
Departs
Mar 23, 2027
from
Buenos Aires, Argentina
Up to 1 deal
7-night south america cruise
$1,016
50% Off List
MSC Cruises –
MSC Virtuosa
Departs
Mar 24, 2027
from
MACEIO
Up to 1 deal
8-night south america cruise
$1,499
49% Off List
MSC Cruises –
MSC Splendida
Departs
Mar 26, 2027
from
Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$1,018
49% Off List
MSC Cruises –
MSC Virtuosa
Departs
Mar 27, 2027
from
Santos, Brazil
Up to 1 deal
3-night south america cruise
$453
50% Off List
MSC Cruises –
MSC Musica
Departs
Mar 29, 2027
from
Santos, Brazil
Up to 1 deal
4-night south america cruise
$546
MSC Cruises –
MSC Virtuosa
Departs
Mar 30, 2027
from
Salvador, Brazil
Up to 1 deal
3-night south america cruise
$408
MSC Cruises –
MSC Virtuosa
Departs
Mar 31, 2027
from
MACEIO
Up to 1 deal
4-night south america cruise
$389
MSC Cruises –
MSC Virtuosa
Departs
Apr 03, 2027
from
Santos, Brazil
Up to 1 deal
4-night south america cruise
$869
MSC Cruises –
MSC Divina
Departs
Mar 14, 2027
from
Santos, Brazil
Up to 1 deal
4-night south america cruise
$289
MSC Cruises –
MSC Musica
Departs
Apr 01, 2027
from
Santos, Brazil
Up to 1 deal
4-night south america cruise
Call Us
MSC Cruises –
MSC Preziosa
Departs
Apr 02, 2026
from
Santos, Brazil
Up to 1 deal
1-night south america cruise
Call Us
MSC Cruises –
MSC Preziosa
Departs
Apr 02, 2026
from
Santos, Brazil
Up to 1 deal
4-night south america cruise
Call Us
MSC Cruises –
MSC Musica
Departs
Nov 16, 2026
from
Santos, Brazil
Up to 1 deal
3-night south america cruise
Call Us
MSC Cruises –
MSC Musica
Departs
Nov 30, 2026
from
Santos, Brazil
Up to 1 deal
4-night south america cruise
Call Us
MSC Cruises –
MSC Musica
Departs
Dec 06, 2026
from
Santos, Brazil
Up to 1 deal
9-night south america cruise
Call Us
MSC Cruises –
MSC Musica
Departs
Dec 28, 2026
from
Santos, Brazil
Up to 1 deal
8-night south america cruise
Call Us
MSC Cruises –
MSC Divina
Departs
Jan 23, 2027
from
Santos, Brazil
7-night south america cruise
Call Us
MSC Cruises –
MSC Musica
Departs
Jan 24, 2027
from
ITAJAI
Up to 1 deal
8-night south america cruise
Call Us
MSC Cruises –
MSC Divina
Departs
Jan 24, 2027
from
CAMBORIU
7-night south america cruise
Call Us
MSC Cruises –
MSC Musica
Departs
Jan 26, 2027
from
Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
Call Us
MSC Cruises –
MSC Divina
Departs
Jan 28, 2027
from
Buenos Aires, Argentina