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Best Panama Canal Cruises

Showing 1-25 of 179 results
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12-night panama canal cruise
$1,352
Princess Cruises – Caribbean Princess
4.1 (257)
Departs Dec 29, 2026 from Fort Lauderdale, Florida
Up to 5 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
12-night panama canal cruise
$1,183
Princess Cruises – Caribbean Princess
4.1 (257)
Departs Jan 22, 2027 from Fort Lauderdale, Florida
Up to 5 deals including an Avoya Exclusive
Secret Rate
Avoya Exclusive Rate
12-night panama canal cruise
$1,152
Princess Cruises – Caribbean Princess
4.1 (257)
Departs Feb 15, 2027 from Fort Lauderdale, Florida
Up to 6 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
10-night panama canal cruise
$4,099
50% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Mar 15, 2027 from Panama City (Fuerte Amador), Panama
Up to 4 deals including an Avoya Exclusive
Secret Rate
16-night panama canal cruise
$1,699
Princess Cruises – Star Princess
4.5 (2)
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 6 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
16-night panama canal cruise
$2,099
Princess Cruises – Island Princess
4.2 (157)
Departs Jan 29, 2027 from San Diego, California
Up to 6 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
11-night panama canal cruise
$1,469
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Feb 06, 2027 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
12-night panama canal cruise
$1,779
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Mar 01, 2027 from Miami, Florida
Up to 10 deals including Avoya Exclusives
Avoya Exclusive Rate
11-night panama canal cruise
$1,319
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Mar 13, 2027 from Miami, Florida
Up to 10 deals including Avoya Exclusives
12-night panama canal cruise
$1,519
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Mar 24, 2027 from Miami, Florida
Up to 10 deals including Avoya Exclusives
14-night panama canal cruise
$2,034
Holland America – Eurodam
4.3 (283)
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
11-night panama canal cruise
$1,759
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Apr 05, 2027 from Miami, Florida
Up to 10 deals including Avoya Exclusives
19-night panama canal cruise
$2,389
Norwegian Cruise Line – Norwegian Bliss
4.0 (126)
Departs Apr 09, 2027 from New York City, New York
Up to 10 deals including Avoya Exclusives
22-night panama canal cruise
$2,609
Norwegian Cruise Line – Norwegian Bliss
4.0 (126)
Departs Apr 09, 2027 from New York City, New York
Up to 10 deals including Avoya Exclusives
15-night panama canal cruise
$2,099
Norwegian Cruise Line – Norwegian Joy
4.1 (97)
Departs Apr 21, 2027 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
20-night panama canal cruise + tour
$3,108
Norwegian Cruise Line – Norwegian Joy
4.1 (97)
Departs Sep 28, 2027 from Los Angeles, California
Up to 6 deals including an Avoya Exclusive
17-night panama canal cruise
$2,289
Norwegian Cruise Line – Norwegian Joy
4.1 (97)
Departs Sep 30, 2027 from Los Angeles, California
Up to 7 deals including an Avoya Exclusive
21-night panama canal cruise
$2,969
Holland America – Eurodam
4.3 (283)
Departs Oct 02, 2027 from Seattle, Washington
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
20-night panama canal cruise + tour
$3,008
Norwegian Cruise Line – Norwegian Bliss
4.0 (126)
Departs Oct 17, 2027 from Los Angeles, California
Up to 7 deals including Avoya Exclusives
17-night panama canal cruise
$2,189
Norwegian Cruise Line – Norwegian Bliss
4.0 (126)
Departs Oct 19, 2027 from Los Angeles, California
Up to 9 deals including Avoya Exclusives
20-night panama canal cruise
$2,449
Norwegian Cruise Line – Norwegian Bliss
4.0 (126)
Departs Oct 19, 2027 from Los Angeles, California
Up to 9 deals including Avoya Exclusives
10-night panama canal cruise
$1,439
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Nov 09, 2027 from Miami, Florida
Up to 6 deals including an Avoya Exclusive
11-night panama canal cruise
$1,969
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Nov 19, 2027 from Miami, Florida
Up to 6 deals including an Avoya Exclusive
11-night panama canal cruise
$1,519
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Nov 30, 2027 from Miami, Florida
Up to 6 deals including an Avoya Exclusive
11-night panama canal cruise
$1,539
Norwegian Cruise Line – Norwegian Jewel
4.4 (174)
Departs Dec 09, 2027 from Miami, Florida
Up to 7 deals including an Avoya Exclusive
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Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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