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No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees. Plus, our Low Price Guarantee! No Avoya Fees on Cruises or Tours.
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MSC Cruises to South America
MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.
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7-night south america cruise
$1,163
50% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 25, 2026
from
Salvador, Brazil
Up to 3 deals
8-night south america cruise
$1,336
50% Off List
MSC Cruises –
MSC Preziosa
Departs
Feb 25, 2026
from
Buenos Aires, Argentina
Up to 2 deals
8-night south america cruise
$2,479
49% Off List
MSC Cruises –
MSC Fantasia
Departs
Feb 25, 2026
from
Montevideo, Uruguay
Up to 3 deals
8-night south america cruise
$1,924
49% Off List
MSC Cruises –
MSC Fantasia
Departs
Feb 26, 2026
from
Buenos Aires, Argentina
Up to 3 deals
4-night south america cruise
$759
50% Off List
MSC Cruises –
MSC Sinfonia
Departs
Feb 27, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,160
50% Off List
MSC Cruises –
MSC Armonia
Departs
Feb 28, 2026
from
Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,288
49% Off List
MSC Cruises –
MSC Seaview
Departs
Feb 28, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,066
49% Off List
MSC Cruises –
MSC Preziosa
Departs
Mar 01, 2026
from
Santos, Brazil
Up to 3 deals
3-night south america cruise
$717
50% Off List
MSC Cruises –
MSC Sinfonia
Departs
Mar 03, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,112
50% Off List
MSC Cruises –
MSC Seaview
Departs
Mar 03, 2026
from
Salvador, Brazil
Up to 2 deals
7-night south america cruise
$1,316
44% Off List
MSC Cruises –
MSC Armonia
Departs
Mar 03, 2026
from
MACEIO
Up to 3 deals
7-night south america cruise
$1,006
49% Off List
MSC Cruises –
MSC Armonia
Departs
Mar 04, 2026
from
Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,061
50% Off List
MSC Cruises –
MSC Seaview
Departs
Mar 04, 2026
from
MACEIO
Up to 2 deals
7-night south america cruise
$1,479
49% Off List
MSC Cruises –
MSC Preziosa
Departs
Mar 05, 2026
from
Buenos Aires, Argentina
Up to 3 deals
4-night south america cruise
$824
50% Off List
MSC Cruises –
MSC Sinfonia
Departs
Mar 06, 2026
from
Santos, Brazil
Up to 2 deals
9-night south america cruise
$2,043
49% Off List
MSC Cruises –
MSC Fantasia
Departs
Mar 06, 2026
from
Buenos Aires, Argentina
Up to 3 deals
7-night south america cruise
$1,107
49% Off List
MSC Cruises –
MSC Seaview
Departs
Mar 07, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,427
MSC Cruises –
MSC Armonia
Departs
Mar 07, 2026
from
Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,060
49% Off List
MSC Cruises –
MSC Preziosa
Departs
Mar 08, 2026
from
Santos, Brazil
Up to 3 deals
3-night south america cruise
$754
47% Off List
MSC Cruises –
MSC Sinfonia
Departs
Mar 10, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,049
52% Off List
MSC Cruises –
MSC Seaview
Departs
Mar 10, 2026
from
Salvador, Brazil
Up to 2 deals
7-night south america cruise
$1,061
50% Off List
MSC Cruises –
MSC Seaview
Departs
Mar 11, 2026
from
MACEIO
Up to 2 deals
7-night south america cruise
$1,251
24% Off List
MSC Cruises –
MSC Preziosa
Departs
Mar 12, 2026
from
Buenos Aires, Argentina
Up to 3 deals
4-night south america cruise
$803
49% Off List
MSC Cruises –
MSC Sinfonia
Departs
Mar 13, 2026
from
Santos, Brazil
Up to 2 deals
1-night south america cruise
$89
MSC Cruises –
MSC Armonia
Departs
Mar 14, 2026
from
Rio de Janeiro, Brazil