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cruises to south america

MSC Cruises to South America

MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.

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7-night south america cruise
$1,306
48% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 12, 2027 from Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,296
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 13, 2027 from MACEIO
Up to 3 deals
9-night south america cruise
$2,242
34% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Jan 14, 2027 from Buenos Aires, Argentina
Up to 3 deals
7-night south america cruise
$1,076
46% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Jan 17, 2027 from ITAJAI
Up to 3 deals
7-night south america cruise
$1,166
49% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Jan 19, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,246
48% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 20, 2027 from MACEIO
Up to 3 deals
7-night south america cruise
$976
49% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Jan 23, 2027 from Paranagua, Brazil
Up to 3 deals
7-night south america cruise
$1,269
48% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 23, 2027 from Santos, Brazil
Up to 3 deals
7-night south america cruise
$956
49% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Jan 24, 2027 from ITAJAI
Up to 3 deals
7-night south america cruise
$1,256
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 26, 2027 from Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,316
48% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 27, 2027 from MACEIO
Up to 3 deals
7-night south america cruise
$1,319
48% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 30, 2027 from Santos, Brazil
Up to 3 deals
7-night south america cruise
$1,286
49% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Jan 31, 2027 from ITAJAI
Up to 3 deals
7-night south america cruise
$976
49% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 02, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,516
48% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 02, 2027 from Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,239
43% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 06, 2027 from Santos, Brazil
Up to 3 deals
7-night south america cruise
$1,056
49% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 07, 2027 from ITAJAI
Up to 3 deals
3-night south america cruise
$589
MSC Cruises – MSC Divina
3.8 (92)
Departs Feb 09, 2027 from Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,066
48% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 09, 2027 from Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,136
48% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 09, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$896
49% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 13, 2027 from Paranagua, Brazil
Up to 3 deals
7-night south america cruise
$876
48% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 14, 2027 from ITAJAI
Up to 3 deals
7-night south america cruise
$1,379
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 14, 2027 from Santos, Brazil
Up to 2 deals
7-night south america cruise
$909
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 16, 2027 from Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,417
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 18, 2027 from Buenos Aires, Argentina
Up to 2 deals
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