No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees. No Avoya Fees.
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No Avoya Fees on Cruises or Tours. Book, change, or cancel without paying any Avoya fees. No Avoya Fees.
Click Here!
MSC Cruises to South America
MSC Cruises South America cruise vacations provide guests with a chance to experience a South American cruise in Italian style and elegance. MSC Cruises to South America introduce travelers to the sights and sounds of the region, from the serenity of private beaches to the bustling city life of Rio de Janeiro, and provide excellent ships that rival the finest hotels in Italy. Onboard MSC Cruise Line, passengers can relax in on-deck swimming pools, enjoy fine Italian 7-course meals, or enjoy an evening show for the family. With all MSC Cruises to South America, kids sail free, making this a valuable family choice.
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1-night south america cruise
$103
MSC Cruises –
MSC Divina
Departs
Nov 15, 2026
from
Rio de Janeiro, Brazil
Up to 3 deals
4-night south america cruise
$536
50% Off List
MSC Cruises –
MSC Musica
Departs
Nov 16, 2026
from
Santos, Brazil
Up to 4 deals
3-night south america cruise
$688
49% Off List
MSC Cruises –
MSC Musica
Departs
Nov 20, 2026
from
Santos, Brazil
Up to 4 deals
3-night south america cruise
$408
49% Off List
MSC Cruises –
MSC Musica
Departs
Nov 23, 2026
from
Santos, Brazil
Up to 4 deals
4-night south america cruise
$526
50% Off List
MSC Cruises –
MSC Musica
Departs
Nov 26, 2026
from
Santos, Brazil
Up to 3 deals
4-night south america cruise
$719
MSC Cruises –
MSC Virtuosa
Departs
Nov 28, 2026
from
Salvador, Brazil
Up to 3 deals
3-night south america cruise
$529
MSC Cruises –
MSC Seaview
Departs
Nov 29, 2026
from
Santos, Brazil
Up to 3 deals
4-night south america cruise
$609
50% Off List
MSC Cruises –
MSC Divina
Departs
Nov 29, 2026
from
Santos, Brazil
Up to 4 deals
3-night south america cruise
$409
49% Off List
MSC Cruises –
MSC Musica
Departs
Nov 30, 2026
from
Santos, Brazil
Up to 4 deals
1-night south america cruise
$100
MSC Cruises –
MSC Virtuosa
Departs
Dec 01, 2026
from
Rio de Janeiro, Brazil
Up to 3 deals
3-night south america cruise
$448
59% Off List
MSC Cruises –
MSC Virtuosa
Departs
Dec 02, 2026
from
Santos, Brazil
Up to 4 deals
3-night south america cruise
$559
MSC Cruises –
MSC Seaview
Departs
Dec 02, 2026
from
Santos, Brazil
Up to 3 deals
3-night south america cruise
$408
49% Off List
MSC Cruises –
MSC Musica
Departs
Dec 03, 2026
from
Santos, Brazil
Up to 4 deals
8-night south america cruise
$1,839
35% Off List
MSC Cruises –
MSC Splendida
Departs
Dec 03, 2026
from
Buenos Aires, Argentina
Up to 4 deals
3-night south america cruise
$605
MSC Cruises –
MSC Virtuosa
Departs
Dec 05, 2026
from
Santos, Brazil
Up to 3 deals
4-night south america cruise
$677
MSC Cruises –
MSC Virtuosa
Departs
Dec 05, 2026
from
Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,079
48% Off List
MSC Cruises –
MSC Virtuosa
Departs
Dec 05, 2026
from
Santos, Brazil
Up to 4 deals
8-night south america cruise
$1,129
MSC Cruises –
MSC Seaview
Departs
Dec 05, 2026
from
Santos, Brazil
Up to 3 deals
4-night south america cruise
$526
50% Off List
MSC Cruises –
MSC Musica
Departs
Dec 06, 2026
from
Santos, Brazil
Up to 4 deals
8-night south america cruise
$1,109
MSC Cruises –
MSC Seaview
Departs
Dec 06, 2026
from
CAMBORIU
Up to 3 deals
8-night south america cruise
$1,581
50% Off List
MSC Cruises –
MSC Splendida
Departs
Dec 06, 2026
from
Rio de Janeiro, Brazil
Up to 4 deals
7-night south america cruise
$1,276
49% Off List
MSC Cruises –
MSC Virtuosa
Departs
Dec 08, 2026
from
Salvador, Brazil
Up to 4 deals
7-night south america cruise
$1,186
49% Off List
MSC Cruises –
MSC Virtuosa
Departs
Dec 09, 2026
from
MACEIO
Up to 4 deals
3-night south america cruise
$468
40% Off List
MSC Cruises –
MSC Musica
Departs
Dec 10, 2026
from
Santos, Brazil
Up to 4 deals
7-night south america cruise
$1,417
MSC Cruises –
MSC Seaview
Departs
Dec 10, 2026
from
Buenos Aires, Argentina
Up to 3 deals