Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!
Home
cruises to mediterranean

MSC Cruises to Mediterranean

Onboard MSC Cruises Mediterranean cruises, guests can relax in Italian style and comfort as they view colorful seaside villages and breathtaking vistas from their verandah. MSC Cruises to the Mediterranean stretch to far-reaching destinations including Alexandria, Casablanca, Dubrovnik, Istanbul, and Marseilles. A Mediterranean cruise with MSC Cruise Line is an exciting adventure through a destination rich with culture and beauty with the advantage of being in the cruise line’s own backyard. 

Showing 326-350 of 3,425 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
9-night mediterranean cruise
$1,459
56% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Aug 31, 2026 from Piraeus (Athens), Greece
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,379
47% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Sep 01, 2026 from Barcelona, Spain
Up to 4 deals
9-night mediterranean cruise
$1,779
47% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Sep 02, 2026 from Istanbul, Turkey
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,052
47% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Sep 03, 2026 from Naples, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,006
49% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Sep 04, 2026 from Ancona, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,028
50% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Sep 04, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,230
46% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Sep 04, 2026 from BRINDISI
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$940
54% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Sep 05, 2026 from Bari, Italy
Up to 4 deals including an Avoya Exclusive
7-night mediterranean cruise
$953
51% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Sep 05, 2026 from Venice, Italy
Up to 5 deals including an Avoya Exclusive
9-night mediterranean cruise
$1,646
53% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Sep 05, 2026 from Bari, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,160
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Sep 06, 2026 from Venice, Italy
Up to 5 deals including an Avoya Exclusive
9-night mediterranean cruise
$1,477
56% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Sep 06, 2026 from Trieste, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,069
51% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Sep 08, 2026 from Piraeus (Athens), Greece
Up to 4 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,266
46% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Sep 08, 2026 from Barcelona, Spain
Up to 4 deals
7-night mediterranean cruise
$905
47% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Sep 09, 2026 from Genoa, Italy
Up to 4 deals
7-night mediterranean cruise
$1,127
50% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Sep 10, 2026 from Naples, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,400
37% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Sep 10, 2026 from Barcelona, Spain
Up to 3 deals
10-night mediterranean cruise
$1,645
42% Off List
MSC Cruises – MSC Opera
4.0 (5)
Departs Sep 10, 2026 from Genoa, Italy
Up to 4 deals
7-night mediterranean cruise
$832
56% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Sep 11, 2026 from Ancona, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$898
53% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Sep 11, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,174
47% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Sep 11, 2026 from BRINDISI
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,070
53% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Sep 13, 2026 from Venice, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,251
52% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Sep 14, 2026 from Kusadasi, Turkey
Up to 5 deals including an Avoya Exclusive
9-night mediterranean cruise
$1,569
51% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs Sep 14, 2026 from Bari, Italy
Up to 5 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,147
49% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Sep 15, 2026 from Piraeus (Athens), Greece
Up to 4 deals including an Avoya Exclusive
Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada:
1-888-447-8459

International: +1-760-305-5070
Avoya Travel.
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo