Menu
Call
No Avoya Fees. Click Here!
Home
cruises to mediterranean

MSC Cruises to Mediterranean

Onboard MSC Cruises Mediterranean cruises, guests can relax in Italian style and comfort as they view colorful seaside villages and breathtaking vistas from their verandah. MSC Cruises to the Mediterranean stretch to far-reaching destinations including Alexandria, Casablanca, Dubrovnik, Istanbul, and Marseilles. A Mediterranean cruise with MSC Cruise Line is an exciting adventure through a destination rich with culture and beauty with the advantage of being in the cruise line’s own backyard. 

Showing 1-25 of 2,554 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
7-night mediterranean cruise
$531
66% Off List
MSC Cruises – MSC Magnifica
4.3 (13)
Departs Nov 22, 2026 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$912
57% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Apr 10, 2027 from Venice, Italy
Up to 3 deals
7-night mediterranean cruise
$774
63% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Apr 16, 2027 from Ancona, Italy
Up to 3 deals
7-night mediterranean cruise
$800
63% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Apr 17, 2027 from Venice, Italy
Up to 3 deals
7-night mediterranean cruise
$821
54% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Apr 23, 2027 from Ancona, Italy
Up to 3 deals
7-night mediterranean cruise
$891
56% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Apr 24, 2027 from Bari, Italy
Up to 3 deals
7-night mediterranean cruise
$743
61% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs Apr 30, 2027 from Ancona, Italy
Up to 3 deals
7-night mediterranean cruise
$769
60% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs May 01, 2027 from Venice, Italy
Up to 3 deals
7-night mediterranean cruise
$1,070
57% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs May 03, 2027 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$928
57% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs May 04, 2027 from Piraeus (Athens), Greece
Up to 3 deals
10-night mediterranean cruise
$1,693
48% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs May 05, 2027 from Alicante, Spain
Up to 3 deals
7-night mediterranean cruise
$1,022
52% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs May 06, 2027 from Palermo, Italy
Up to 3 deals
7-night mediterranean cruise
$778
59% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs May 07, 2027 from Ancona, Italy
Up to 3 deals
10-night mediterranean cruise
$1,682
48% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs May 07, 2027 from Rome (Civitavecchia), Italy
Up to 3 deals
7-night mediterranean cruise
$769
60% Off List
MSC Cruises – MSC Lirica
4.3 (6)
Departs May 08, 2027 from Venice, Italy
Up to 3 deals
7-night mediterranean cruise
$917
57% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs May 08, 2027 from Bari, Italy
Up to 3 deals
9-night mediterranean cruise
$1,308
58% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs May 09, 2027 from Bari, Italy
Up to 3 deals
7-night mediterranean cruise
$1,052
41% Off List
MSC Cruises – MSC Fantasia
3.8 (12)
Departs May 11, 2027 from Livorno, Italy
Up to 3 deals
9-night mediterranean cruise
$1,288
58% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs May 13, 2027 from Piraeus (Athens), Greece
Up to 3 deals
7-night mediterranean cruise
$892
59% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs May 15, 2027 from Bari, Italy
Up to 3 deals
10-night mediterranean cruise
$1,682
48% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs May 17, 2027 from Rome (Civitavecchia), Italy
Up to 3 deals
7-night mediterranean cruise
$1,464
41% Off List
MSC Cruises – MSC World Asia
Departs May 18, 2027 from Messina, Italy
Up to 2 deals
10-night mediterranean cruise
$1,702
48% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs May 18, 2027 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$986
54% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs May 22, 2027 from Bari, Italy
Up to 3 deals
9-night mediterranean cruise
$1,308
58% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs May 22, 2027 from Piraeus (Athens), Greece
Up to 3 deals
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. …103
  7. Next
Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada:
1-888-447-8459

International: +1-760-305-5070
Avoya Travel.
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo