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Best South America Cruises

Showing 176-200 of 545 results
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17-night south america cruise
$13,800
Silversea – Silver Shadow
4.5 (40)
Departs Jan 29, 2028 from Santiago (Valparaiso), Chile
Up to 2 deals including an Avoya Exclusive
22-night south america cruise
$4,684
Holland America – Oosterdam
4.2 (212)
Departs Jan 30, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
15-night south america cruise
$2,889
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Feb 01, 2028 from San Antonio, Chile
12-night south america cruise
$12,900
Silversea – Silver Shadow
4.5 (40)
Departs Feb 15, 2028 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
15-night south america cruise
$2,859
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Feb 16, 2028 from Buenos Aires, Argentina
12-night south america cruise
$11,440
Silversea – Silver Ray
5.0 (3)
Departs Feb 17, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
14-night south america cruise
$2,414
Holland America – Oosterdam
4.2 (212)
Departs Feb 21, 2028 from San Antonio, Chile
Up to 1 deal including an Avoya Exclusive
19-night south america cruise
$9,100
Silversea – Silver Shadow
4.5 (40)
Departs Feb 27, 2028 from Rio de Janeiro, Brazil
Up to 2 deals including an Avoya Exclusive
20-night south america cruise
$15,330
Silversea – Silver Ray
5.0 (3)
Departs Feb 29, 2028 from Rio de Janeiro, Brazil
Up to 1 deal including an Avoya Exclusive
15-night south america cruise
$2,499
Holland America – Oosterdam
4.2 (212)
Departs Mar 06, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
31-night south america cruise
$5,014
Holland America – Oosterdam
4.2 (212)
Departs Mar 06, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
16-night south america cruise
$2,809
Holland America – Oosterdam
4.2 (212)
Departs Mar 21, 2028 from San Antonio, Chile
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$9,799
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Feb 05, 2026 from Buenos Aires, Argentina
7-night south america cruise
$1,349
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 07, 2026 from Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,546
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 07, 2026 from Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,824
50% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 08, 2026 from Santos, Brazil
Up to 3 deals
3-night south america cruise
$790
49% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 10, 2026 from Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,169
60% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 10, 2026 from Salvador, Brazil
Up to 2 deals
7-night south america cruise
$1,309
49% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 10, 2026 from MACEIO
Up to 3 deals
7-night south america cruise
$1,550
49% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 11, 2026 from Salvador, Brazil
Up to 3 deals
7-night south america cruise
$1,704
50% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 11, 2026 from MACEIO
Up to 2 deals
4-night south america cruise
$817
49% Off List
MSC Cruises – MSC Sinfonia
4.0 (3)
Departs Feb 13, 2026 from Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,238
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Feb 14, 2026 from Santos, Brazil
Up to 2 deals
7-night south america cruise
$1,483
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Feb 14, 2026 from Rio de Janeiro, Brazil
Up to 3 deals
7-night south america cruise
$1,728
50% Off List
MSC Cruises – MSC Preziosa
3.9 (7)
Departs Feb 15, 2026 from Santos, Brazil
Up to 3 deals

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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