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Best South America Cruises

Showing 151-175 of 529 results
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12-night south america cruise
$11,195
4% Off List
Viking Ocean Cruises – Viking Polaris
5.0 (1)
Departs Nov 13, 2026 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
12-night south america cruise
$9,995
Viking Ocean Cruises – Viking Octantis
4.7 (9)
Departs Nov 23, 2026 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$10,499
5% Off List
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Dec 02, 2026 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$9,699
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Dec 19, 2026 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$10,899
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Jan 05, 2027 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$10,999
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Jan 22, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$10,999
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Feb 08, 2027 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
29-night south america cruise
$5,999
Holland America – Zaandam
4.5 (132)
Departs Feb 13, 2027 from Buenos Aires, Argentina
Up to 1 deal
17-night south america cruise
$10,499
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Feb 25, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
13-night south america cruise
$17,995
Viking Ocean Cruises – Viking Polaris
5.0 (1)
Departs Mar 10, 2027 from Ushuaia, Argentina
Up to 1 deal including an Avoya Exclusive
17-night south america cruise
$15,995
Viking Ocean Cruises – Viking Polaris
5.0 (1)
Departs Mar 22, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
19-night south america cruise
$10,995
8% Off List
Viking Ocean Cruises – Viking Octantis
4.7 (9)
Departs Apr 01, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
22-night south america cruise
$4,969
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Jan 08, 2028 from San Antonio, Chile
Up to 2 deals
22-night south america cruise
$4,869
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Jan 30, 2028 from Buenos Aires, Argentina
Up to 2 deals
14-night south america cruise
$2,439
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Feb 21, 2028 from San Antonio, Chile
Up to 2 deals
15-night south america cruise
$2,674
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Mar 06, 2028 from Buenos Aires, Argentina
Up to 2 deals
32-night south america cruise
$5,129
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Mar 06, 2028 from Buenos Aires, Argentina
Up to 2 deals
17-night south america cruise
$2,894
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Mar 21, 2028 from San Antonio, Chile
Up to 2 deals
10-night south america cruise + tour
$8,098
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Nov 12, 2026 from San Antonio, Chile
Up to 2 deals
Secret Rate
30-night south america cruise + tour
$32,397
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Nov 12, 2026 from San Antonio, Chile
Up to 2 deals
Secret Rate
1-night south america cruise
$103
MSC Cruises – MSC Divina
3.8 (92)
Departs Nov 15, 2026 from Rio de Janeiro, Brazil
Up to 3 deals including an Avoya Exclusive
4-night south america cruise
$525
50% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Nov 16, 2026 from Santos, Brazil
Up to 4 deals including an Avoya Exclusive
21-night south america cruise + tour
$26,997
Seabourn – Seabourn Venture
5.0 (2)
Departs Nov 18, 2026 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate
3-night south america cruise
$443
50% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Nov 20, 2026 from Santos, Brazil
Up to 3 deals including an Avoya Exclusive
21-night south america cruise + tour
$26,997
Seabourn – Seabourn Pursuit
5.0 (1)
Departs Nov 21, 2026 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Secret Rate

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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