Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

Best South America Cruises

Showing 126-150 of 447 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
12-night south america cruise
$11,400
Silversea – Silver Ray
5.0 (3)
Departs Feb 17, 2028 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive
19-night south america cruise
$10,500
Silversea – Silver Shadow
4.5 (40)
Departs Feb 27, 2028 from Rio de Janeiro, Brazil
Up to 2 deals including an Avoya Exclusive
20-night south america cruise
$15,500
Silversea – Silver Ray
5.0 (3)
Departs Feb 29, 2028 from Rio de Janeiro, Brazil
Up to 1 deal including an Avoya Exclusive
15-night south america cruise
$3,239
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Mar 02, 2028 from San Antonio, Chile
Up to 1 deal
31-night south america cruise
$4,379
Holland America – Oosterdam
4.2 (212)
Departs Nov 18, 2026 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
30-night south america cruise
$4,699
Holland America – Volendam
4.3 (73)
Departs Nov 22, 2026 from New York City, New York
Up to 2 deals including an Avoya Exclusive
15-night south america cruise
$2,599
Holland America – Oosterdam
4.2 (212)
Departs Dec 04, 2026 from San Antonio, Chile
Up to 2 deals including an Avoya Exclusive
22-night south america cruise
$5,039
Holland America – Oosterdam
4.2 (212)
Departs Dec 19, 2026 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
41-night south america cruise
$10,284
Holland America – Zaandam
4.5 (132)
Departs Jan 03, 2027 from Fort Lauderdale, Florida
Up to 1 deal
70-night south america cruise
$15,614
Holland America – Zaandam
4.5 (132)
Departs Jan 03, 2027 from Fort Lauderdale, Florida
Up to 1 deal
22-night south america cruise
$4,899
Holland America – Oosterdam
4.2 (212)
Departs Jan 10, 2027 from San Antonio, Chile
Up to 2 deals including an Avoya Exclusive
29-night south america cruise
$6,769
Holland America – Zaandam
4.5 (132)
Departs Feb 13, 2027 from Buenos Aires, Argentina
Up to 1 deal
14-night south america cruise
$2,119
Holland America – Oosterdam
4.2 (212)
Departs Feb 23, 2027 from San Antonio, Chile
Up to 2 deals including an Avoya Exclusive
26-night south america cruise
$3,479
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 07, 2027 from Vancouver, BC, Canada
41-night south america cruise
$5,424
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 07, 2027 from Vancouver, BC, Canada
21-night south america cruise
$2,909
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 12, 2027 from San Diego, California
36-night south america cruise
$4,904
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 12, 2027 from San Diego, California
15-night south america cruise
$2,284
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Nov 02, 2027 from San Antonio, Chile
15-night south america cruise
$2,284
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Nov 17, 2027 from Buenos Aires, Argentina
15-night south america cruise
$2,459
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Dec 02, 2027 from San Antonio, Chile
22-night south america cruise
$4,509
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Dec 17, 2027 from Buenos Aires, Argentina
28-night south america cruise
$5,979
Holland America – Zuiderdam
4.3 (156)
Departs Jan 06, 2028 from Fort Lauderdale, Florida
Up to 1 deal including an Avoya Exclusive
22-night south america cruise
$4,659
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Jan 08, 2028 from San Antonio, Chile
22-night south america cruise
$4,684
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Jan 30, 2028 from Buenos Aires, Argentina
14-night south america cruise
$2,414
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Feb 21, 2028 from San Antonio, Chile

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada:
1-888-447-8459

International: +1-760-305-5070
Avoya Travel.
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo