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Best South America Cruises

Showing 126-150 of 492 results
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7-night south america cruise
$5,698
AmaWaterways – AmaMelodia
Departs Feb 17, 2027 from Barranquilla, Colombia
Up to 1 deal
16-night south america cruise
$14,200
Silversea – Silver Nova
5.0 (5)
Departs Feb 17, 2027 from Buenos Aires, Argentina
Up to 1 deal
14-night south america cruise
$2,399
Holland America – Oosterdam
4.2 (212)
Departs Feb 23, 2027 from San Antonio, Chile
Up to 3 deals including an Avoya Exclusive
7-night south america cruise
$6,398
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Feb 27, 2027 from Cartagena, Spain
Up to 1 deal
11-night south america cruise
$9,400
Silversea – Silver Cloud
4.3 (16)
Departs Feb 27, 2027 from Puerto Williams, Chile
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
$5,748
AmaWaterways – AmaMelodia
Departs Mar 10, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$4,649
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Mar 20, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$5,348
AmaWaterways – AmaMelodia
Departs Mar 31, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$4,698
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Apr 10, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$3,899
AmaWaterways – AmaMelodia
Departs Apr 14, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$3,899
AmaWaterways – AmaMelodia
Departs Apr 21, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$3,549
AmaWaterways – AmaMelodia
Departs May 26, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$3,549
AmaWaterways – AmaMelodia
Departs Jun 02, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$3,649
AmaWaterways – AmaMelodia
Departs Jun 09, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$3,649
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Jun 12, 2027 from Barranquilla, Colombia
Up to 1 deal
26-night south america cruise
$3,309
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 07, 2027 from Vancouver, BC, Canada
Up to 2 deals including an Avoya Exclusive
41-night south america cruise
$4,934
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 07, 2027 from Vancouver, BC, Canada
Up to 2 deals including an Avoya Exclusive
21-night south america cruise
$2,884
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 12, 2027 from San Diego, California
Up to 2 deals including an Avoya Exclusive
36-night south america cruise
$4,529
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Oct 12, 2027 from San Diego, California
Up to 2 deals including an Avoya Exclusive
7-night south america cruise
$4,598
AmaWaterways – AmaMelodia
Departs Oct 20, 2027 from Cartagena, Spain
15-night south america cruise
$2,124
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Nov 02, 2027 from San Antonio, Chile
Up to 2 deals including an Avoya Exclusive
15-night south america cruise
$2,024
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Nov 17, 2027 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
7-night south america cruise
$3,999
AmaWaterways – AmaMelodia
Departs Dec 15, 2027 from Cartagena, Spain
14-night south america cruise
$8,000
Silversea – Silver Shadow
4.5 (40)
Departs Jan 15, 2028 from Cartagena, Colombia
Up to 2 deals including an Avoya Exclusive
12-night south america cruise
$8,600
Silversea – Silver Ray
5.0 (3)
Departs Jan 15, 2028 from Miami, Florida
Up to 1 deal including an Avoya Exclusive

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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