Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

Best South America Cruises

Showing 76-100 of 492 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
7-night south america cruise
$3,499
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Jan 30, 2027 from Cartagena, Spain
22-night south america cruise
$5,099
Holland America – Oosterdam
4.2 (212)
Departs Feb 01, 2027 from Buenos Aires, Argentina
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
21-night south america cruise
$13,099
50% Off List
Oceania Cruises – Insignia
4.3 (171)
Departs Feb 14, 2027 from Santiago (Valparaiso), Chile
Up to 5 deals including an Avoya Exclusive
Secret Rate
18-night south america cruise
$13,000
Silversea – Silver Nova
5.0 (5)
Departs Mar 05, 2027 from Santiago (Valparaiso), Chile
Up to 2 deals including an Avoya Exclusive
15-night south america cruise
$2,499
Holland America – Oosterdam
4.2 (212)
Departs Mar 09, 2027 from Buenos Aires, Argentina
Up to 4 deals including Avoya Exclusives
22-night south america cruise
$19,099
57% Off List
Regent Cruises – Seven Seas Grandeur
5.0 (3)
Departs Mar 09, 2027 from Panama City (Fuerte Amador), Panama
Up to 2 deals including an Avoya Exclusive
16-night south america cruise
$12,099
60% Off List
Regent Cruises – Seven Seas Mariner
4.5 (103)
Departs Mar 10, 2027 from Lima (Callao), Peru
Up to 2 deals including an Avoya Exclusive
7-night south america cruise
$5,748
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Mar 13, 2027 from Cartagena, Spain
Up to 1 deal
16-night south america cruise
$2,299
Holland America – Oosterdam
4.2 (212)
Departs Mar 24, 2027 from San Antonio, Chile
Up to 4 deals including Avoya Exclusives
7-night south america cruise
$5,198
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Mar 27, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$4,299
AmaWaterways – AmaMelodia
Departs Apr 07, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$4,348
AmaWaterways – AmaMagdalena
5.0 (1)
Departs May 01, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$3,799
AmaWaterways – AmaMagdalena
5.0 (1)
Departs May 08, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$3,549
AmaWaterways – AmaMelodia
Departs May 12, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$3,549
AmaWaterways – AmaMagdalena
5.0 (1)
Departs May 15, 2027 from Barranquilla, Colombia
Up to 1 deal
7-night south america cruise
$3,549
AmaWaterways – AmaMelodia
Departs May 19, 2027 from Cartagena, Spain
7-night south america cruise
$3,649
AmaWaterways – AmaMelodia
Departs Jun 16, 2027 from Cartagena, Spain
Up to 1 deal
7-night south america cruise
$4,448
AmaWaterways – AmaMagdalena
5.0 (1)
Departs Jun 26, 2027 from Barranquilla, Colombia
Up to 1 deal
15-night south america cruise
$2,799
Princess Cruises – Majestic Princess
4.3 (66)
Departs Nov 21, 2027 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
15-night south america cruise
$2,599
Princess Cruises – Majestic Princess
4.3 (66)
Departs Dec 06, 2027 from San Antonio, Chile
Up to 5 deals including an Avoya Exclusive
16-night south america cruise
$3,919
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Dec 17, 2027 from Buenos Aires, Argentina
Up to 2 deals
17-night south america cruise
$3,149
Princess Cruises – Majestic Princess
4.3 (66)
Departs Dec 21, 2027 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
15-night south america cruise
$3,009
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Jan 02, 2028 from San Antonio, Chile
Up to 2 deals
17-night south america cruise
$3,039
Princess Cruises – Majestic Princess
4.3 (66)
Departs Jan 07, 2028 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
15-night south america cruise
$3,059
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Jan 17, 2028 from Buenos Aires, Argentina
Up to 2 deals

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada:
1-888-447-8459

International: +1-760-305-5070
Avoya Travel.
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo