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Best South America Cruises

Showing 726-750 of 821 results
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27-night south america cruise
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Holland America – Volendam
4.3 (74)
Departs Nov 25, 2026 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Dec 12, 2026 from Barranquilla, Colombia
Up to 2 deals
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Dec 19, 2026 from Cartagena, Colombia
Up to 2 deals
41-night south america cruise
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Holland America – Zaandam
4.5 (133)
Departs Jan 03, 2027 from Fort Lauderdale, Florida
Avoya Exclusive Rate
70-night south america cruise
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Holland America – Zaandam
4.5 (133)
Departs Jan 03, 2027 from Fort Lauderdale, Florida
22-night south america cruise
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Holland America – Oosterdam
4.2 (213)
Departs Feb 01, 2027 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Jan 05, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Jan 15, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Jan 29, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Feb 16, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Feb 26, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Mar 08, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Mar 11, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Mar 15, 2028 from Barranquilla, Colombia
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Mar 22, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Mar 25, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Mar 29, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Apr 05, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Apr 12, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Apr 15, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Apr 19, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs Apr 26, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMagdalena
5.0 (1)
Departs Apr 29, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs May 03, 2028 from Cartagena, Colombia
Up to 1 deal including an Avoya Exclusive
7-night south america cruise
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AmaWaterways – AmaMelodia
Departs May 10, 2028 from Barranquilla, Colombia
Up to 1 deal including an Avoya Exclusive

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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