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Best South America Cruises

Showing 626-650 of 859 results
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4-night south america cruise
$479
49% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Feb 21, 2028 from Santos, Brazil
7-night south america cruise
$929
49% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Feb 21, 2028 from CAMBORIU
8-night south america cruise
$929
50% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Feb 21, 2028 from Buenos Aires, Argentina
7-night south america cruise
$2,687
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 21, 2028 from Puerto Caldera (Puntarenas), Costa Rica
Up to 1 deal
14-night south america cruise
$5,468
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 21, 2028 from Puerto Caldera (Puntarenas), Costa Rica
Up to 1 deal
21-night south america cruise
$7,942
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 21, 2028 from Puerto Caldera (Puntarenas), Costa Rica
Up to 1 deal
7-night south america cruise
$904
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 22, 2028 from Salvador, Brazil
7-night south america cruise
$904
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 23, 2028 from MACEIO
8-night south america cruise
$924
50% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Feb 24, 2028 from Rio de Janeiro, Brazil
7-night south america cruise
$968
48% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Feb 24, 2028 from Buenos Aires, Argentina
Up to 2 deals
4-night south america cruise
$499
49% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Feb 25, 2028 from Santos, Brazil
7-night south america cruise
$869
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 26, 2028 from Santos, Brazil
7-night south america cruise
$821
50% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 27, 2028 from ITAJAI
Up to 2 deals
7-night south america cruise
$869
49% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Feb 27, 2028 from Santos, Brazil
14-night south america cruise
$2,263
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Feb 27, 2028 from Buenos Aires, Argentina
Up to 4 deals
19-night south america cruise
$9,900
Silversea – Silver Shadow
4.5 (40)
Departs Feb 27, 2028 from Rio de Janeiro, Brazil
Up to 2 deals
7-night south america cruise
$929
49% Off List
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Feb 28, 2028 from CAMBORIU
7-night south america cruise
$3,656
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 28, 2028 from Balboa, Panama
Up to 2 deals including an Avoya Exclusive
19-night south america cruise
$4,268
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Feb 28, 2028 from San Antonio, Chile
Up to 1 deal
14-night south america cruise
$5,535
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 28, 2028 from Balboa, Panama
Up to 2 deals including an Avoya Exclusive
3-night south america cruise
$479
49% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Feb 29, 2028 from Santos, Brazil
7-night south america cruise
$904
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 29, 2028 from Salvador, Brazil
8-night south america cruise
$1,009
50% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Feb 29, 2028 from Buenos Aires, Argentina
11-night south america cruise
$13,100
Silversea – Silver Cloud
4.3 (16)
Departs Feb 29, 2028 from Puerto Williams, Chile
Up to 3 deals including an Avoya Exclusive
7-night south america cruise
$904
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Mar 01, 2028 from MACEIO

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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