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Best South America Cruises

Showing 26-50 of 821 results
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15-night south america cruise
$2,132
Princess Cruises – Majestic Princess
4.4 (68)
Departs Dec 22, 2026 from Santiago (Valparaiso), Chile
Up to 3 deals including an Avoya Exclusive
Secret Rate
17-night south america cruise
$3,947
Princess Cruises – Majestic Princess
4.4 (68)
Departs Jan 06, 2027 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
Secret Rate
11-night south america cruise
$13,699
Regent Cruises – Seven Seas Mariner
4.5 (103)
Departs Jan 22, 2027 from Rio de Janeiro, Brazil
Up to 2 deals including an Avoya Exclusive
17-night south america cruise
$3,595
Princess Cruises – Majestic Princess
4.4 (68)
Departs Jan 23, 2027 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
Secret Rate
21-night south america cruise
$14,849
50% Off List
Oceania Cruises – Insignia
4.3 (172)
Departs Jan 24, 2027 from Buenos Aires, Argentina
Up to 3 deals
12-night south america cruise
$6,249
50% Off List
Oceania Cruises – Insignia
4.3 (172)
Departs Mar 07, 2027 from Buenos Aires, Argentina
Up to 4 deals including an Avoya Exclusive
33-night south america cruise
$14,049
50% Off List
Oceania Cruises – Insignia
4.3 (172)
Departs Mar 07, 2027 from Buenos Aires, Argentina
Up to 4 deals including an Avoya Exclusive
22-night south america cruise
$28,549
Regent Cruises – Seven Seas Grandeur
5.0 (4)
Departs Mar 09, 2027 from Panama City (Fuerte Amador), Panama
Up to 2 deals including an Avoya Exclusive
16-night south america cruise
$12,399
Regent Cruises – Seven Seas Mariner
4.5 (103)
Departs Mar 10, 2027 from Lima (Callao), Peru
Up to 2 deals including an Avoya Exclusive
Secret Rate
14-night south america cruise
$2,493
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Dec 05, 2027 from Buenos Aires, Argentina
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
14-night south america cruise
$2,248
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Dec 19, 2027 from Buenos Aires, Argentina
Up to 3 deals including Avoya Exclusives
14-night south america cruise
$4,690
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Jan 02, 2028 from Buenos Aires, Argentina
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
14-night south america cruise
$5,549
50% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Jan 05, 2028 from Miami, Florida
Up to 4 deals including an Avoya Exclusive
14-night south america cruise
$6,461
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Jan 16, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
14-night south america cruise
$6,161
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Jan 30, 2028 from Buenos Aires, Argentina
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
14-night south america cruise
$2,604
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Feb 13, 2028 from Buenos Aires, Argentina
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
14-night south america cruise
$2,263
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Feb 27, 2028 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
12-night south america cruise
$1,844
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Mar 12, 2028 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
15-night south america cruise
$1,287
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Mar 24, 2028 from Santiago (Valparaiso), Chile
Up to 5 deals including an Avoya Exclusive
15-night south america cruise
$1,280
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Nov 05, 2028 from Los Angeles, California
Up to 5 deals including an Avoya Exclusive
13-night south america cruise
$1,466
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Nov 20, 2028 from Santiago (Valparaiso), Chile
Up to 5 deals including an Avoya Exclusive
14-night south america cruise
$1,852
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Dec 03, 2028 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
16-night south america cruise
$3,630
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Dec 17, 2028 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
12-night south america cruise
$1,693
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Jan 02, 2029 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive
14-night south america cruise
$2,778
Celebrity Cruises – Celebrity Equinox
4.6 (604)
Departs Jan 14, 2029 from Buenos Aires, Argentina
Up to 5 deals including an Avoya Exclusive

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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