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Best South America Cruises

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17-night south america cruise
$2,580
Cunard – Queen Anne
5.0 (1)
Departs Jan 22, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
37-night south america cruise
$7,398
Cunard – Queen Anne
5.0 (1)
Departs Jan 22, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
17-night south america cruise
$10,299
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Jan 22, 2027 from Santiago (Valparaiso), Chile
Up to 1 deal including an Avoya Exclusive
56-night south america cruise
$11,099
Cunard – Queen Anne
5.0 (1)
Departs Jan 22, 2027 from Fort Lauderdale, Florida
Up to 3 deals including Avoya Exclusives
7-night south america cruise
$931
50% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Jan 23, 2027 from Paranagua, Brazil
Up to 1 deal
7-night south america cruise
$1,213
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 23, 2027 from Santos, Brazil
Up to 1 deal
9-night south america cruise
$1,716
49% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Jan 23, 2027 from Buenos Aires, Argentina
Up to 1 deal
7-night south america cruise
$1,211
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 26, 2027 from Salvador, Brazil
Up to 1 deal
9-night south america cruise
$1,609
49% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Jan 26, 2027 from Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$1,264
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 27, 2027 from MACEIO
Up to 1 deal
7-night south america cruise
$1,265
49% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Jan 30, 2027 from Santos, Brazil
Up to 1 deal
7-night south america cruise
$931
50% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Jan 31, 2027 from ITAJAI
Up to 1 deal
7-night south america cruise
$1,061
49% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Jan 31, 2027 from Santos, Brazil
Up to 1 deal
7-night south america cruise
$1,097
50% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Feb 01, 2027 from CAMBORIU
Up to 1 deal
9-night south america cruise
$1,617
49% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Feb 01, 2027 from Buenos Aires, Argentina
Up to 1 deal
7-night south america cruise
$891
50% Off List
MSC Cruises – MSC Musica
3.5 (4)
Departs Feb 02, 2027 from Rio de Janeiro, Brazil
Up to 1 deal
7-night south america cruise
$1,264
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 02, 2027 from Salvador, Brazil
Up to 1 deal
7-night south america cruise
$1,211
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 03, 2027 from MACEIO
Up to 1 deal
9-night south america cruise
$1,889
49% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Feb 04, 2027 from Rio de Janeiro, Brazil
Up to 1 deal
12-night south america cruise
$8,910
Explora Journeys – Explora I
5.0 (4)
Departs Feb 05, 2027 from San Juan, Puerto Rico
Up to 5 deals including Avoya Exclusives
7-night south america cruise
$2,069
50% Off List
MSC Cruises – MSC Virtuosa
5.0 (1)
Departs Feb 06, 2027 from Santos, Brazil
Up to 1 deal
7-night south america cruise
$1,075
49% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Feb 07, 2027 from Santos, Brazil
Up to 1 deal
7-night south america cruise
$1,024
50% Off List
MSC Cruises – MSC Divina
3.8 (92)
Departs Feb 08, 2027 from CAMBORIU
Up to 1 deal
20-night south america cruise
$4,635
Cunard – Queen Anne
5.0 (1)
Departs Feb 08, 2027 from Rio de Janeiro, Brazil
Up to 3 deals including Avoya Exclusives
17-night south america cruise
$10,499
Viking Ocean Cruises – Viking Jupiter
4.6 (28)
Departs Feb 08, 2027 from Buenos Aires, Argentina
Up to 1 deal including an Avoya Exclusive

South America Cruises Overview

Experience the lifestyles and cultures in South America by enjoying rain forests, palm trees, sprawling cities, and several natural wonders. South America is filled with lively metropolitan cities, mysterious caves and canyons, and more, and a cruise to South America is one of the best ways to explore this spectacular continent.

Cruises through South America take guests to a variety of ports in countries including Argentina, Brazil, and Chile. Several sailings will also take travelers around the southern tip of South America and along the coast of Antarctica, where passengers can view the icy glaciers of the remote continent and striking wildlife including penguins and whales.

Passengers can visit the mansions of Palermo in the elegant city of Buenos Aires, Argentina; the skyscrapers in the bustling city of Santiago, Chile; the colonial architecture in the stunning city of Lima, Peru; and more. Travelers can also enjoy a night out in the vibrant city of Rio de Janeiro in Brazil while experiencing the invigorating lifestyle of locals, and the string of volcanoes on the Galapagos Islands, which provides travelers with views of tortoises, flamingos, and iguanas.

Local cuisine consists of hefty meals including meat and potatoes, flat bread, chorizo, tasty fruit juices, and more. Cruisers can also learn traditional dances such as the tango, and gain insight into the historical stories and customs of the local gauchos. With so many cultures and sights, cruising around South America allows travelers to sample and experience a diverse mixture of everything the colorful continent has to offer.

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