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Best Panama Canal Cruises

Showing 151-175 of 229 results
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21-night panama canal cruise
$1,589
Cunard – Queen Elizabeth
4.1 (35)
Departs Sep 24, 2026 from Seattle, Washington
Up to 3 deals including Avoya Exclusives
21-night panama canal cruise
$2,234
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Sep 27, 2026 from Vancouver, BC, Canada
Up to 1 deal including an Avoya Exclusive
20-night panama canal cruise
$2,109
Holland America – Eurodam
4.3 (283)
Departs Oct 04, 2026 from Vancouver, BC, Canada
Up to 2 deals including an Avoya Exclusive
16-night panama canal cruise
$1,779
Holland America – Eurodam
4.3 (283)
Departs Oct 08, 2026 from San Diego, California
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$5,169
Windstar Cruises – Wind Star
4.6 (89)
Departs Dec 05, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
8-night panama canal cruise
$3,465
Windstar Cruises – Star Legend
4.5 (86)
Departs Dec 12, 2026 from Oranjestad, Aruba
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$4,069
Windstar Cruises – Wind Star
4.6 (89)
Departs Dec 12, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
16-night panama canal cruise
$5,227
Windstar Cruises – Star Legend
4.5 (86)
Departs Dec 12, 2026 from Oranjestad, Aruba
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$4,169
Windstar Cruises – Wind Star
4.6 (89)
Departs Dec 19, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
8-night panama canal cruise
$2,761
Windstar Cruises – Star Legend
4.5 (86)
Departs Dec 20, 2026 from Balboa, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$4,769
Windstar Cruises – Wind Star
4.6 (89)
Departs Dec 26, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$4,669
Windstar Cruises – Wind Star
4.6 (89)
Departs Jan 02, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$3,557
Windstar Cruises – Star Legend
4.5 (86)
Departs Jan 12, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$3,657
Windstar Cruises – Star Legend
4.5 (86)
Departs Jan 19, 2027 from Colon, Panama
Up to 1 deal
7-night panama canal cruise
$3,857
Windstar Cruises – Star Legend
4.5 (86)
Departs Jan 26, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
8-night panama canal cruise
$4,669
Windstar Cruises – Wind Star
4.6 (89)
Departs Jan 31, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
36-night panama canal cruise
$12,205
Windstar Cruises – Wind Star
4.6 (89)
Departs Jan 31, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$3,857
Windstar Cruises – Star Legend
4.5 (86)
Departs Feb 02, 2027 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$2,661
Windstar Cruises – Star Legend
4.5 (86)
Departs Feb 09, 2027 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
6-night panama canal cruise
$3,465
Windstar Cruises – Star Legend
4.5 (86)
Departs Feb 16, 2027 from Balboa, Panama
14-night panama canal cruise
$5,985
Windstar Cruises – Star Legend
4.5 (86)
Departs Feb 16, 2027 from Balboa, Panama
Up to 2 deals including an Avoya Exclusive
20-night panama canal cruise
$2,384
Holland America – Eurodam
4.3 (283)
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
21-night panama canal cruise
$2,534
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Apr 11, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
32-night panama canal cruise
$1,950
Cunard – Queen Elizabeth
4.1 (35)
Departs Apr 02, 2026 from Miami, Florida
Up to 2 deals including an Avoya Exclusive
42-night panama canal cruise
$2,610
Cunard – Queen Elizabeth
4.1 (35)
Departs Apr 02, 2026 from Miami, Florida
Up to 2 deals including an Avoya Exclusive

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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