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Best Panama Canal Cruises

Showing 126-150 of 229 results
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16-night panama canal cruise
$7,999
Oceania Cruises – Sonata
Departs Dec 19, 2027 from Miami, Florida
11-night panama canal cruise
$1,988
Celebrity Cruises – Celebrity Ascent
5.0 (22)
Departs Jan 03, 2028 from Fort Lauderdale, Florida
Up to 4 deals
16-night panama canal cruise
$7,899
Oceania Cruises – Sonata
Departs Jan 06, 2028 from Los Angeles, California
11-night panama canal cruise
$2,137
Celebrity Cruises – Celebrity Ascent
5.0 (22)
Departs Feb 14, 2028 from Fort Lauderdale, Florida
Up to 4 deals
11-night panama canal cruise
$2,154
Celebrity Cruises – Celebrity Ascent
5.0 (22)
Departs Mar 27, 2028 from Fort Lauderdale, Florida
Up to 4 deals
8-night panama canal cruise
$3,083
Windstar Cruises – Wind Surf
4.7 (148)
Departs Feb 09, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$3,396
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 09, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
19-night panama canal cruise
$5,948
Windstar Cruises – Wind Surf
4.7 (148)
Departs Feb 09, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
15-night panama canal cruise
$10,749
Norwegian Cruise Line – Norwegian Jade
4.2 (153)
Departs Feb 12, 2026 from San Diego, California
Up to 8 deals including an Avoya Exclusive
7-night panama canal cruise
$3,236
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 16, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
7-night panama canal cruise
$3,316
Windstar Cruises – Star Pride
4.5 (95)
Departs Feb 23, 2026 from Colon, Panama
Up to 3 deals including Avoya Exclusives
6-night panama canal cruise
$2,418
Windstar Cruises – Star Pride
4.5 (95)
Departs Mar 09, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
22-night panama canal cruise
$2,429
Holland America – Eurodam
4.3 (283)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 1 deal including an Avoya Exclusive
26-night panama canal cruise
$2,614
Holland America – Eurodam
4.3 (283)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 1 deal including an Avoya Exclusive
27-night panama canal cruise
$2,734
Holland America – Eurodam
4.3 (283)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 1 deal including an Avoya Exclusive
29-night panama canal cruise
$3,229
Holland America – Koningsdam
4.2 (239)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 1 deal including an Avoya Exclusive
34-night panama canal cruise
$3,509
Holland America – Koningsdam
4.2 (239)
Departs Mar 29, 2026 from Fort Lauderdale, Florida
Up to 1 deal including an Avoya Exclusive
19-night panama canal cruise
$2,269
Holland America – Eurodam
4.3 (283)
Departs Apr 05, 2026 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
22-night panama canal cruise
$2,299
Holland America – Koningsdam
4.2 (239)
Departs Apr 10, 2026 from Fort Lauderdale, Florida
Up to 1 deal including an Avoya Exclusive
7-night panama canal cruise
$5,853
Windstar Cruises – Star Seeker
Departs Apr 13, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
15-night panama canal cruise
$9,578
Windstar Cruises – Star Seeker
Departs Apr 13, 2026 from Colon, Panama
Up to 2 deals including an Avoya Exclusive
20-night panama canal cruise
$1,430
Cunard – Queen Elizabeth
4.1 (35)
Departs Apr 14, 2026 from Miami, Florida
Up to 3 deals including Avoya Exclusives
8-night panama canal cruise
$3,314
Windstar Cruises – Star Seeker
Departs Apr 20, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$5,743
Windstar Cruises – Star Seeker
Departs Apr 20, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive
25-night panama canal cruise
$15,104
Windstar Cruises – Star Seeker
Departs Apr 20, 2026 from Puerto Caldera (Puntarenas), Costa Rica
Up to 2 deals including an Avoya Exclusive

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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