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Best Panama Canal Cruises

Showing 101-125 of 179 results
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16-night panama canal cruise
$1,409
Princess Cruises – Island Princess
4.2 (157)
Departs Dec 13, 2027 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
15-night panama canal cruise
$2,674
Holland America – Zaandam
4.5 (133)
Departs Dec 18, 2027 from San Diego, California
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$7,515
55% Off List
Oceania Cruises – Sonata
Departs Dec 19, 2027 from Miami, Florida
Up to 3 deals including an Avoya Exclusive
25-night panama canal cruise
$13,149
63% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Dec 19, 2027 from Miami, Florida
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$12,199
61% Off List
Regent Cruises – Seven Seas Splendor
4.3 (31)
Departs Dec 20, 2027 from Miami, Florida
Up to 4 deals including an Avoya Exclusive
14-night panama canal cruise
$10,549
62% Off List
Regent Cruises – Seven Seas Grandeur
5.0 (4)
Departs Dec 22, 2027 from Miami, Florida
Up to 3 deals including an Avoya Exclusive
12-night panama canal cruise
$1,799
Princess Cruises – Caribbean Princess
4.1 (257)
Departs Dec 23, 2027 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$1,499
Princess Cruises – Island Princess
4.2 (157)
Departs Dec 29, 2027 from Los Angeles, California
Up to 4 deals including an Avoya Exclusive
11-night panama canal cruise
$2,290
Celebrity Cruises – Celebrity Ascent
5.0 (22)
Departs Jan 03, 2028 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
14-night panama canal cruise
$17,999
58% Off List
Regent Cruises – Seven Seas Voyager
4.5 (82)
Departs Jan 13, 2028 from Miami, Florida
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$1,619
Princess Cruises – Island Princess
4.2 (157)
Departs Mar 02, 2028 from Los Angeles, California
Up to 3 deals including an Avoya Exclusive
12-night panama canal cruise
$7,549
64% Off List
Regent Cruises – Seven Seas Prestige
Departs Mar 02, 2028 from Miami, Florida
Up to 3 deals including an Avoya Exclusive
11-night panama canal cruise
$2,498
Celebrity Cruises – Celebrity Ascent
5.0 (22)
Departs Mar 27, 2028 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
22-night panama canal cruise
$3,409
Holland America – Eurodam
4.3 (283)
Departs Apr 01, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$1,949
Princess Cruises – Star Princess
4.5 (2)
Departs Apr 07, 2028 from Port Canaveral, Florida
Up to 3 deals including an Avoya Exclusive
21-night panama canal cruise
$3,434
Holland America – Oosterdam
4.2 (213)
Departs Apr 07, 2028 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
16-night panama canal cruise
$1,799
Princess Cruises – Island Princess
4.2 (157)
Departs Apr 19, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
21-night panama canal cruise
$2,379
Princess Cruises – Island Princess
4.2 (157)
Departs Apr 19, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
20-night panama canal cruise
$2,019
Princess Cruises – Emerald Princess
4.2 (199)
Departs Apr 22, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$2,024
Princess Cruises – Ruby Princess
4.2 (224)
Departs Aug 28, 2028 from San Francisco, California
20-night panama canal cruise
$2,323
Princess Cruises – Coral Princess
4.4 (127)
Departs Sep 20, 2028 from Vancouver, BC, Canada
16-night panama canal cruise
$1,874
Princess Cruises – Coral Princess
4.4 (127)
Departs Sep 24, 2028 from San Diego, California
16-night panama canal cruise
$1,824
Princess Cruises – Ruby Princess
4.2 (224)
Departs Oct 03, 2028 from Fort Lauderdale, Florida
16-night panama canal cruise
$1,984
Princess Cruises – Star Princess
4.5 (2)
Departs Oct 12, 2028 from Los Angeles, California
11-night panama canal cruise
$7,999
64% Off List
Regent Cruises – Seven Seas Prestige
Departs Dec 09, 2028 from Miami, Florida
Up to 3 deals including an Avoya Exclusive

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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