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Best Panama Canal Cruises

Showing 76-100 of 179 results
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10-night panama canal cruise
$3,249
50% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Mar 05, 2028 from Miami, Florida
Up to 4 deals including an Avoya Exclusive
12-night panama canal cruise
$7,349
64% Off List
Regent Cruises – Seven Seas Prestige
Departs Mar 14, 2028 from Panama City (Fuerte Amador), Panama
Up to 3 deals including an Avoya Exclusive
26-night panama canal cruise
$17,299
64% Off List
Regent Cruises – Seven Seas Prestige
Departs Mar 14, 2028 from Panama City (Fuerte Amador), Panama
Up to 3 deals including an Avoya Exclusive
10-night panama canal cruise
$3,149
50% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Mar 15, 2028 from Panama City (Fuerte Amador), Panama
Up to 4 deals including an Avoya Exclusive
19-night panama canal cruise
$2,529
Norwegian Cruise Line – Norwegian Bliss
4.0 (126)
Departs Apr 14, 2028 from New York City, New York
Up to 8 deals including an Avoya Exclusive
22-night panama canal cruise
$2,839
Norwegian Cruise Line – Norwegian Bliss
4.0 (126)
Departs Apr 14, 2028 from New York City, New York
Up to 8 deals including an Avoya Exclusive
15-night panama canal cruise
$2,029
Norwegian Cruise Line – Norwegian Joy
4.1 (97)
Departs Apr 17, 2028 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
16-night panama canal cruise
$1,599
Princess Cruises – Emerald Princess
4.2 (199)
Departs Apr 22, 2028 from Fort Lauderdale, Florida
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
11-night panama canal cruise
$14,899
Regent Cruises – Seven Seas Prestige
Departs Feb 22, 2027 from Panama City (Fuerte Amador), Panama
Up to 3 deals including an Avoya Exclusive
20-night panama canal cruise
$2,254
Holland America – Eurodam
4.3 (283)
Departs Apr 03, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
21-night panama canal cruise
$2,249
Holland America – Nieuw Amsterdam
4.3 (198)
Departs Apr 11, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
23-night panama canal cruise
$2,477
Princess Cruises – Island Princess
4.2 (157)
Departs Apr 19, 2027 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
18-night panama canal cruise
$2,429
Celebrity Cruises – Celebrity Summit
4.5 (379)
Departs Sep 18, 2027 from Los Angeles, California
Up to 4 deals including an Avoya Exclusive
23-night panama canal cruise
$3,214
Princess Cruises – Coral Princess
4.4 (127)
Departs Sep 22, 2027 from Vancouver, BC, Canada
Up to 3 deals including an Avoya Exclusive
18-night panama canal cruise
$2,094
Princess Cruises – Coral Princess
4.4 (127)
Departs Sep 27, 2027 from Los Angeles, California
Up to 3 deals including an Avoya Exclusive
23-night panama canal cruise
$2,043
Princess Cruises – Star Princess
4.5 (2)
Departs Oct 03, 2027 from Vancouver, BC, Canada
Up to 4 deals including an Avoya Exclusive
20-night panama canal cruise
$2,949
Holland America – Eurodam
4.3 (283)
Departs Oct 03, 2027 from Vancouver, BC, Canada
Up to 3 deals including an Avoya Exclusive
23-night panama canal cruise
$2,503
Princess Cruises – Island Princess
4.2 (157)
Departs Oct 06, 2027 from Vancouver, BC, Canada
Up to 2 deals including an Avoya Exclusive
16-night panama canal cruise
$2,769
Holland America – Eurodam
4.3 (283)
Departs Oct 07, 2027 from San Diego, California
Up to 3 deals including an Avoya Exclusive
16-night panama canal cruise
$1,349
Princess Cruises – Star Princess
4.5 (2)
Departs Oct 10, 2027 from Los Angeles, California
Up to 4 deals including an Avoya Exclusive
32-night panama canal cruise
$16,549
50% Off List
Oceania Cruises – Vista
4.7 (37)
Departs Oct 10, 2027 from Montreal, Quebec, Canada
Up to 4 deals including an Avoya Exclusive
16-night panama canal cruise
$1,579
Princess Cruises – Island Princess
4.2 (157)
Departs Oct 13, 2027 from Los Angeles, California
Up to 4 deals including an Avoya Exclusive
16-night panama canal cruise
$1,349
Princess Cruises – Emerald Princess
4.2 (199)
Departs Oct 24, 2027 from Los Angeles, California
Up to 4 deals including an Avoya Exclusive
12-night panama canal cruise
$1,949
Princess Cruises – Caribbean Princess
4.1 (257)
Departs Nov 11, 2027 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
29-night panama canal cruise
$14,249
50% Off List
Oceania Cruises – Sonata
Departs Dec 06, 2027 from Miami, Florida
Up to 3 deals including an Avoya Exclusive

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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