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Best Panama Canal Cruises

Showing 26-50 of 179 results
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10-night panama canal cruise
$1,439
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Dec 11, 2027 from Miami, Florida
Up to 6 deals including an Avoya Exclusive
12-night panama canal cruise
$2,389
Norwegian Cruise Line – Norwegian Gem
4.2 (150)
Departs Dec 21, 2027 from Miami, Florida
Up to 5 deals including an Avoya Exclusive
14-night panama canal cruise
$2,559
Holland America – Zaandam
4.5 (133)
Departs Jan 16, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
12-night panama canal cruise
$1,600
Princess Cruises – Caribbean Princess
4.1 (257)
Departs Feb 12, 2028 from Fort Lauderdale, Florida
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
16-night panama canal cruise
$2,769
Holland America – Eurodam
4.3 (283)
Departs Apr 01, 2028 from Fort Lauderdale, Florida
Up to 3 deals including an Avoya Exclusive
Avoya Exclusive Rate
15-night panama canal cruise
$2,624
Holland America – Oosterdam
4.2 (213)
Departs Apr 07, 2028 from Fort Lauderdale, Florida
Up to 2 deals including an Avoya Exclusive
Avoya Exclusive Rate
15-night panama canal cruise
$1,331
Royal Caribbean – Serenade of the Seas
4.5 (214)
Departs Apr 22, 2028 from Tampa, Florida
Up to 2 deals including an Avoya Exclusive
Secret Rate
Avoya Exclusive Rate
12-night panama canal cruise
$649
Princess Cruises – Caribbean Princess
4.1 (257)
Departs Dec 05, 2026 from Fort Lauderdale, Florida
Up to 4 deals including Avoya Exclusives
Secret Rate
Avoya Exclusive Rate
12-night panama canal cruise
$1,569
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Dec 21, 2026 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
Avoya Exclusive Rate
11-night panama canal cruise
$1,159
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Jan 02, 2027 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
12-night panama canal cruise
$1,459
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Jan 13, 2027 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
16-night panama canal cruise
$1,799
Princess Cruises – Island Princess
4.2 (157)
Departs Jan 13, 2027 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
Secret Rate
Avoya Exclusive Rate
16-night panama canal cruise
$17,799
Regent Cruises – Seven Seas Grandeur
5.0 (4)
Departs Jan 24, 2027 from Los Angeles, California
Up to 3 deals including Avoya Exclusives
12-night panama canal cruise
$1,569
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Jan 25, 2027 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
Avoya Exclusive Rate
19-night panama canal cruise + tour
$2,638
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Feb 11, 2027 from San Diego, California
Up to 5 deals including an Avoya Exclusive
16-night panama canal cruise
$1,709
Norwegian Cruise Line – Norwegian Star
4.1 (162)
Departs Feb 13, 2027 from San Diego, California
Up to 5 deals including an Avoya Exclusive
16-night panama canal cruise
$2,559
Princess Cruises – Island Princess
4.2 (157)
Departs Feb 14, 2027 from Fort Lauderdale, Florida
Up to 4 deals including an Avoya Exclusive
Secret Rate
12-night panama canal cruise
$1,799
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Feb 17, 2027 from Miami, Florida
Up to 8 deals including an Avoya Exclusive
14-night panama canal cruise
$11,299
61% Off List
Regent Cruises – Seven Seas Grandeur
5.0 (4)
Departs Feb 23, 2027 from Miami, Florida
Up to 3 deals including Avoya Exclusives
10-night panama canal cruise
$3,799
50% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Mar 05, 2027 from Miami, Florida
Up to 4 deals including an Avoya Exclusive
Secret Rate
16-night panama canal cruise
$1,509
Princess Cruises – Island Princess
4.2 (157)
Departs Mar 18, 2027 from Fort Lauderdale, Florida
Up to 5 deals including an Avoya Exclusive
Secret Rate
Avoya Exclusive Rate
16-night panama canal cruise
$2,009
Princess Cruises – Island Princess
4.2 (157)
Departs Apr 03, 2027 from Los Angeles, California
Up to 5 deals including an Avoya Exclusive
Secret Rate
Avoya Exclusive Rate
16-night panama canal cruise
$1,449
Princess Cruises – Crown Princess
4.3 (211)
Departs Apr 04, 2027 from Fort Lauderdale, Florida
Up to 5 deals including an Avoya Exclusive
Secret Rate
18-night panama canal cruise
$6,637
62% Off List
Oceania Cruises – Vista
4.7 (37)
Departs Oct 24, 2027 from Miami, Florida
Up to 5 deals including an Avoya Exclusive
Secret Rate
11-night panama canal cruise
$619
Norwegian Cruise Line – Norwegian Sun
4.1 (156)
Departs Nov 18, 2026 from Miami, Florida
Up to 8 deals including an Avoya Exclusive

Panama Canal Cruises Overview

Almost 100 years after it was created in 1916, the Panama Canal not only serves as a connection between the Pacific and Atlantic Oceans, but also provides views of jungles, endangered species, pristine beaches, and more. Travelers have the chance to see exotic wildlife such as crocodiles, monkeys, sloths, and toucans while traversing the entire canal from Florida to the West coast, with stops in ports along the Caribbean, Mexican Riviera, and Central and South America.

The Panama Canal and its neighboring destinations have a variety of adventures for travelers. Surrounded by vast jungle, cruisers can trek through green, cloudy mountains while marveling at orchid gardens and distant volcanoes. The white sandy shores of several ports will entice cruisers to spend afternoons on the beach, after snorkeling, scuba diving, and kayaking through teal waters.

Passengers can explore the shipwreck of Antilla in Aruba; shop in Puerto Vallarta, Mexico; snorkel with the stingrays at the Stingray Sandbar in the Caymen Islands; enjoy the Aerial Tram ride through Costa Rica's rain forests; admire cliff divers in Acapulco; and more.

Travelers will want to pack a good pair of binoculars to use on the cruise deck when traveling through the tropical setting and fascinating sights of the Panama Canal. Cruises crossing the canal and stopping at nearby destinations provide the ultimate vacation filled with adventure, relaxation, and the opportunity to watch astounding views while lounging on deck or one's private balcony.

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