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Best Mediterranean Cruises

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7-night mediterranean cruise
$4,322
52% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Sep 26, 2026 from Istanbul, Turkey
Up to 4 deals including an Avoya Exclusive
7-night europe cruise
$1,459
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Sep 27, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night mediterranean cruise
$1,727
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Sep 28, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
12-night mediterranean cruise
$3,420
52% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Sep 30, 2026 from Barcelona, Spain
Up to 6 deals including Avoya Exclusives
9-night mediterranean cruise
$2,710
55% Off List
Oceania Cruises – Marina
4.5 (399)
Departs Oct 02, 2026 from Bilbao, Spain
Up to 4 deals including an Avoya Exclusive
Secret Rate
14-night mediterranean cruise
$11,549
62% Off List
Regent Cruises – Seven Seas Navigator
4.3 (72)
Departs Oct 02, 2026 from Istanbul, Turkey
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,074
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Oct 03, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
11-night mediterranean cruise
$2,304
Holland America – Oosterdam
4.2 (212)
Departs Oct 03, 2026 from Piraeus (Athens), Greece
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$4,249
50% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Oct 03, 2026 from Trieste, Italy
Up to 4 deals including an Avoya Exclusive
7-night europe cruise
$1,385
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Oct 04, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night mediterranean cruise
$1,290
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Oct 05, 2026 from Piraeus (Athens), Greece
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$2,649
50% Off List
Oceania Cruises – Insignia
4.3 (171)
Departs Oct 06, 2026 from Barcelona, Spain
Up to 4 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,334
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Oct 11, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night mediterranean cruise
$1,675
62% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Oct 12, 2026 from Rome (Civitavecchia), Italy
Up to 6 deals including an Avoya Exclusive
Secret Rate
10-night mediterranean cruise
$3,499
50% Off List
Oceania Cruises – Insignia
4.3 (171)
Departs Oct 13, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,042
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Oct 17, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$1,134
Princess Cruises – Sun Princess
4.3 (7)
Departs Oct 17, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
Secret Rate
14-night mediterranean cruise
$6,770
55% Off List
Oceania Cruises – Allura
5.0 (2)
Departs Oct 17, 2026 from Istanbul, Turkey
Up to 4 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,484
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Oct 18, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night europe cruise
$1,147
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Oct 19, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
10-night mediterranean cruise
$2,145
64% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Oct 19, 2026 from Monte Carlo, Monaco
Up to 6 deals including an Avoya Exclusive
Secret Rate
10-night mediterranean cruise
$2,742
57% Off List
Oceania Cruises – Insignia
4.3 (171)
Departs Oct 23, 2026 from Venice, Italy
Up to 6 deals including an Avoya Exclusive
Secret Rate
7-night europe cruise
$962
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Oct 24, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
12-night mediterranean cruise
$1,957
Princess Cruises – Sky Princess
4.3 (64)
Departs Oct 24, 2026 from Southampton, United Kingdom
Up to 6 deals including Avoya Exclusives
Secret Rate
11-night mediterranean cruise
$2,018
Holland America – Oosterdam
4.2 (212)
Departs Oct 24, 2026 from Piraeus (Athens), Greece
Up to 3 deals including Avoya Exclusives
Avoya Exclusive Rate

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

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