Menu
Call
No Avoya Fees on Cruises or Tours. Click Here!

Best Mediterranean Cruises

Showing 351-375 of 6,633 results
Meet Natalie Thompson, one of Avoya's trusted travel advisors.
Our team has helped more than 2.5 million travelers save time, save money, and book their perfect vacation.
Choose your adventure and let us handle the rest.
Your dedicated Personal Travel Advisor is here to help you plan the vacation of your dreams. From finding the best price to answering every question, we are with you every step of the way at no extra cost.
Help Me Plan
7-night mediterranean cruise
$1,419
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Aug 23, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night europe cruise
$1,295
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Aug 24, 2026 from Piraeus (Athens), Greece
Up to 4 deals including Avoya Exclusives
14-night mediterranean cruise
$4,050
55% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Aug 27, 2026 from Istanbul, Turkey
Up to 5 deals including an Avoya Exclusive
13-night mediterranean cruise
$7,499
Atlas Ocean Voyages – World Traveller
4.5 (100)
Departs Aug 27, 2026 from Piraeus (Athens), Greece
Up to 2 deals including an Avoya Exclusive
7-night mediterranean cruise
$1,221
Holland America – Oosterdam
4.2 (212)
Departs Aug 29, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals including Avoya Exclusives
Avoya Exclusive Rate
14-night mediterranean cruise
$3,060
67% Off List
Oceania Cruises – Nautica
4.4 (180)
Departs Aug 30, 2026 from Bilbao, Spain
Up to 6 deals including an Avoya Exclusive
Secret Rate
7-night europe cruise
$1,231
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Aug 31, 2026 from Piraeus (Athens), Greece
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$1,127
Princess Cruises – Enchanted Princess
4.4 (79)
Departs Sep 01, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,254
Princess Cruises – Sun Princess
4.3 (7)
Departs Sep 05, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
Secret Rate
7-night mediterranean cruise
$1,325
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Sep 06, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
7-night mediterranean cruise
$1,396
Royal Caribbean – Brilliance of the Seas
4.4 (159)
Departs Sep 07, 2026 from Rome (Civitavecchia), Italy
Up to 4 deals including Avoya Exclusives
6-night mediterranean cruise
$4,499
Atlas Ocean Voyages – World Traveller
4.5 (100)
Departs Sep 09, 2026 from Rome (Civitavecchia), Italy
Up to 2 deals including an Avoya Exclusive
10-night mediterranean cruise
$2,285
64% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Sep 10, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including an Avoya Exclusive
Secret Rate
7-night mediterranean cruise
$1,123
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Sep 12, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
Avoya Exclusive Rate
11-night mediterranean cruise
$2,209
Holland America – Oosterdam
4.2 (212)
Departs Sep 12, 2026 from Barcelona, Spain
Up to 3 deals including Avoya Exclusives
Avoya Exclusive Rate
10-night mediterranean cruise
$7,499
63% Off List
Regent Cruises – Seven Seas Navigator
4.3 (72)
Departs Sep 12, 2026 from Venice, Italy
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$6,999
Atlas Ocean Voyages – World Traveller
4.5 (100)
Departs Sep 15, 2026 from Dubrovnik, Croatia
Up to 2 deals including an Avoya Exclusive
11-night mediterranean cruise
$9,999
61% Off List
Regent Cruises – Seven Seas Mariner
4.5 (103)
Departs Sep 18, 2026 from Barcelona, Spain
Up to 3 deals including an Avoya Exclusive
7-night mediterranean cruise
$900
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Sep 19, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
7-night europe cruise
$1,428
Royal Caribbean – Odyssey of the Seas
4.6 (90)
Departs Sep 20, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
Avoya Exclusive Rate
10-night mediterranean cruise
$3,199
50% Off List
Oceania Cruises – Sirena
4.3 (140)
Departs Sep 20, 2026 from Valletta, Malta
Up to 5 deals including an Avoya Exclusive
8-night mediterranean cruise
$6,599
Atlas Ocean Voyages – World Traveller
4.5 (100)
Departs Sep 22, 2026 from Venice, Italy
Up to 2 deals including an Avoya Exclusive
10-night mediterranean cruise
$2,094
Holland America – Oosterdam
4.2 (212)
Departs Sep 23, 2026 from Trieste, Italy
Up to 2 deals including Avoya Exclusives
Avoya Exclusive Rate
7-night mediterranean cruise
$931
Royal Caribbean – Explorer of the Seas
4.4 (196)
Departs Sep 26, 2026 from Ravenna, Italy
Up to 4 deals including Avoya Exclusives
7-night mediterranean cruise
$1,144
Princess Cruises – Sun Princess
4.3 (7)
Departs Sep 26, 2026 from Rome (Civitavecchia), Italy
Up to 5 deals including Avoya Exclusives
Secret Rate

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

Latest Articles

Why a Princess Cruise to the Mediterranean Is the Perfect Getaway
From iconic landmarks to awe-inspiring landscapes and culturally rich experiences, you’re bound to have the vacation of a lifetime in the Mediterranean. Better yet, read on to discover all you can experience onboard a Princess cruise to the Mediterranean and why it is the perfect getaway.
Read more

FAQ's

Don't Miss the Latest Deals!
Talk to a Vacation Planner
Avoya Travel Logo Mark
Why Choose Avoya?
U.S. / Canada: 1-888-877-7042
UK: 0-800-098-8475
Australia: 1-800-651-320
International: 001-760-305-5070
Avoya Travel. Beyond The Web.®
CST: 2085569-40
Fla. Seller of Travel Ref. No. ST36781
© Avoya Travel®. All Rights Reserved.
Avoya Travel Logo