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Best Mediterranean Cruises

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7-night mediterranean cruise
$1,181
40% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 13, 2026 from Livorno, Italy
Up to 3 deals
7-night mediterranean cruise
$995
49% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 14, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals
7-night mediterranean cruise
$1,245
47% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 14, 2026 from Valletta, Malta
Up to 3 deals
7-night mediterranean cruise
$1,482
43% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 14, 2026 from Cagliari, Sardinia, Italy
Up to 2 deals
7-night mediterranean cruise
$734
57% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Oct 15, 2026 from Marseille, France
Up to 3 deals
7-night mediterranean cruise
$994
52% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Oct 15, 2026 from Barcelona, Spain
Up to 3 deals
7-night mediterranean cruise
$1,064
47% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 15, 2026 from Palermo, Italy
Up to 3 deals
7-night mediterranean cruise
$816
59% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Oct 16, 2026 from Barcelona (Tarragona), Spain
Up to 3 deals
7-night mediterranean cruise
$907
55% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 16, 2026 from Palma de Mallorca, Spain
Up to 3 deals
7-night mediterranean cruise
$1,035
49% Off List
MSC Cruises – MSC Splendida
4.7 (9)
Departs Oct 16, 2026 from Valletta, Malta
Up to 3 deals
7-night mediterranean cruise
$1,045
57% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 16, 2026 from Barcelona, Spain
Up to 3 deals
7-night mediterranean cruise
$1,370
29% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Oct 16, 2026 from Marseille, France
Up to 3 deals
4-night mediterranean cruise
$502
50% Off List
MSC Cruises – MSC Magnifica
4.3 (13)
Departs Oct 17, 2026 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$795
61% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 17, 2026 from Barcelona, Spain
Up to 3 deals
7-night mediterranean cruise
$895
55% Off List
MSC Cruises – MSC Orchestra
4.0 (4)
Departs Oct 17, 2026 from Valencia, Spain
Up to 3 deals
7-night mediterranean cruise
$987
50% Off List
MSC Cruises – MSC Armonia
3.2 (19)
Departs Oct 17, 2026 from Split, Croatia
Up to 3 deals
7-night mediterranean cruise
$1,137
43% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Oct 17, 2026 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$1,276
45% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 17, 2026 from Marseille, France
Up to 3 deals
4-night mediterranean cruise
$493
45% Off List
MSC Cruises – MSC Magnifica
4.3 (13)
Departs Oct 18, 2026 from Marseille, France
Up to 3 deals
7-night mediterranean cruise
$957
49% Off List
MSC Cruises – MSC Seaview
4.6 (5)
Departs Oct 18, 2026 from Rome (Civitavecchia), Italy
Up to 3 deals
7-night mediterranean cruise
$1,209
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 18, 2026 from Cannes, France
Up to 2 deals
1-night mediterranean cruise
$169
MSC Cruises – MSC Meraviglia
3.8 (89)
Departs Oct 19, 2026 from Marseille, France
Up to 2 deals
4-night mediterranean cruise
$728
40% Off List
MSC Cruises – MSC Magnifica
4.3 (13)
Departs Oct 19, 2026 from Barcelona, Spain
Up to 3 deals
7-night mediterranean cruise
$920
53% Off List
MSC Cruises – MSC Grandiosa
5.0 (2)
Departs Oct 19, 2026 from Genoa, Italy
Up to 3 deals
7-night mediterranean cruise
$1,034
56% Off List
MSC Cruises – MSC World Europa
2.0 (3)
Departs Oct 19, 2026 from Naples, Italy
Up to 3 deals

Mediterranean Cruises Overview

Western and Eastern Mediterranean cruises provide travelers with a magnificent getaway and the perfect combination of pristine beaches and ancient ruins. Scattered along the coast of the Mediterranean are colorful cities and towns that welcome guests with rugged cliffs, charming villages, and picturesque coves.

Springing forth from the history are many different cultures, however, they all share one thing: a relaxed atmosphere that focuses on enjoying 'the good life' by taking time to enjoy amazing food, spend ample time with family, and meander the beaches, vineyards, and hillsides that exist in the fertile countries perched against the Mediterranean Sea's teal waters - all easily explored with Mediterranean cruises.

On a Mediterranean cruise passengers have the chance to focus on a specific port or country, or to sample numerous countries during one trip. Destinations include the shores of Greece, Italy, France, Spain, Turkey, and more. The Italian Riviera's main port, Genoa, captivates travelers with its charming art, intricate alleyways, and 16th century palazzos. Portofino lies between the blue sea and emerald green mountains and enchants visitors with its pastel-colored villages and homes. Another must-see city port in Italy is Naples, featuring the National Archaeological Museum, the ruins of Pompeii, and some of the world's best opera and theater houses. Italy cruises deliver centuries of history, natural beauty, charming people, and more.

Greece cruises explore the beautiful waters and beaches of the Greek Isles which contain 6,000 islands scattered throughout the Aegean and Ionian Seas, of which 227 are inhabited. Greek Island cruises provide excellent opportunities for those who love water sports to windsurf, scuba dive, and sail. Cruising through the Strait of Gibraltar, vacationers can port in Spain and enjoy the plazas and clustered homes of Seville, or marvel at La Sagrada Familia in Barcelona. Spain cruises will please the senses with delicious tapas, fascinating culture, and vibrant cities. In the Eastern Mediterranean, islands sprinkled near the coast of Croatia guide you toward the stone architecture and city walls of Dubrovnik, and Istanbul fascinates vacationers with a plethora of Ottoman mosques and historical buildings.

With exquisite cuisine including the zesty flavors of Spain, the delicate culinary delights of France, and the traditional dishes of Italy, cruisers can experience a variety of cultures with a Mediterranean cruise. Whether you're looking for a relaxed, luxury Mediterranean cruise or a European adventure, one of the Mediterranean Cruise Lines below will suite all your needs on a dream Mediterranean cruise vacation.

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